• …and Chronic Pancreatitis

    Inflammation in chronic pancreatitis can result in the persistent loss of pancreatic tissue, which leads to PEI

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  • …and Pancreatic Cancer

    Tumour growth can cause PEI when it damages the pancreas or obstructs the pancreatic duct

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  • …and Cystic Fibrosis

    Pancreatic secretions become viscous in cystic fibrosis, blocking the release of digestive enzymes and causing PEI

    READ MORE >
  • …and Diabetes

    What is type 3c Diabetes?

    READ MORE >
  • … and Gastrointestinal Surgery

    Anatomical changes after surgery can cause PEI

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  • … and Coeliac Disease

    Chronic inflammation of the small intestine can cause malabsorption of nutrients

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  • … and Irritable Bowel Syndrome (IBS)

    A small proportion of IBS patients also have symptoms of PEI

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  • … and Inflammatory Bowel Disease (IBD)

    IBD is a term that includes Crohn's disease and ulcerative colitis

    READ MORE >

Optimising the Management of Pancreatic Exocrine Insufficiency

Pancreatic exocrine insufficiency (PEI), is a condition in which people are unable to adequately digest fats, carbohydrates and proteins due to a lack of digestive enzymes being produced from the pancreas. This may result in nutrient malabsorption and malnutrition, which can have further consequences for patients.1

PEI is usually associated with other medical conditions, including cystic fibrosis, chronic pancreatitis, pancreatic cancer, diabetes, gastrointestinal surgery, coeliac disease, irritable bowel syndrome, or inflammatory bowel disease.2

This online resource is for healthcare professionals who would like to learn more about PEI, its causes, and its management.

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References

  1. Singh VK, Haupt ME, Geller DE, Hall JA, Quintana Diez PM. Less common etiologies of exocrine pancreatic insufficiency. World J Gastroenterol. 2017;23(39):7059-7076.
  2. Smith RC, Smith SF, Wilson J, Pearce C, Wray N, Vo R, et al. Australasian guidelines for the management of pancreatic exocrine insufficiency. Australasian Pancreatic Club, October 2015. pp 1-122.